MODOK, the Mental Organism Designed Only for Killing, is the product of the corrupt scientists of A.I.M (Advanced Idea Mechanics). Iron Man learns that MODOK has turned his back on his creators, destroying an A.I.M. undersea lab, leaving only one devastated survivor. But MODOK’s fearsome plan involves more than taking revenge…

Now Iron Man must recruit his fellow heroes War Machine, Captain America, and the Black Panther to help him stop MODOK from gathering the materials he needs to create the ultimate weapon—a weapon that could spell humanity’s doom! But MODOK has recruited some help of his own…deadly help!